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EMD-37505

Single-particle
2.71 Å
EMD-37505
3D View Gallery
Deposition: 20/09/2023
Map released: 06/03/2024
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-37505
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8wg8 summary report (pdf.gz) Map and 8wg8 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structures of peptide free and Gs-coupled GCGR

EMD-37505

Single-particle
2.71 Å
EMD-37505
3D View Gallery
Deposition: 20/09/2023
Map released: 06/03/2024
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Rattus norvegicus, Bos taurus, synthetic construct, Spodoptera frugiperda
Sample: Cryo-EM structure of the human glucagon like peptide 1 receptor in complex with tirzepatide and G protein
Fitted models: 8wg8

Deposition Authors: Cong ZT, Zhao FH, Li Y, Luo G, Zhou QT, Yang DH, Wang MW
Molecular features of the ligand-free GLP-1R, GCGR and GIPR in complex with G s proteins.
Cong Z, Zhao F, Li Y, Luo G, Mai Y, Chen X, Chen Y, Lin S, Cai X, Zhou Q , Yang D , Wang MW
(2024) Cell Discov , 10 , 18 - 18
PUBMED: 38346960
DOI: doi:10.1038/s41421-024-00649-0
ISSN: 2056-5968