EMD-37476

Single-particle
3.2 Å
EMD-37476
3D View Gallery
Deposition: 17/09/2023
Map released: 06/12/2023
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-37476

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8wea summary report (pdf.gz) Map-8wea FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Human L-type voltage-gated calcium channel Cav1.2 (Class II) in the presence of pinaverium at 3.2 Angstrom resolution

EMD-37476

Single-particle
3.2 Å
EMD-37476
3D View Gallery
Deposition: 17/09/2023
Map released: 06/12/2023
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Cav1.2
Fitted models: 8wea

Deposition Authors: Gao S, Yao X, Fan X , Yan N
Structural basis for human Ca v 1.2 inhibition by multiple drugs and the neurotoxin calciseptine.
Gao S, Yao X, Chen J, Huang G, Fan X , Xue L , Li Z, Wu T , Zheng Y, Huang J, Jin X, Wang Y, Wang Z, Yu Y, Liu L, Pan X, Song C, Yan N
(2023) Cell , 186 , 5363 - 5374.e16
PUBMED: 37972591
DOI: doi:10.1016/j.cell.2023.10.007
ISSN: 1097-4172