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EMD-37243

Single-particle
3.13 Å
EMD-37243
3D View Gallery
Deposition: 21/08/2023
Map released: 01/05/2024
Last modified: 21/08/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-37243
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8khf summary report (pdf.gz) Map and 8khf FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of the human ATP synthase bound to bedaquiline (membrane domain)

EMD-37243

Single-particle
3.13 Å
EMD-37243
3D View Gallery
Deposition: 21/08/2023
Map released: 01/05/2024
Last modified: 21/08/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: human ATP synthase
Fitted models: 8khf

Deposition Authors: Lai Y, Zhang Y, Gong H
Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587.
Zhang Y, Lai Y, Zhou S, Ran T , Zhang Y, Zhao Z, Feng Z, Yu L, Xu J, Shi K, Wang J, Pang Y, Li L, Chen H, Guddat LW , Gao Y , Liu F , Rao Z, Gong H
(2024) Nature , 631 , 409 - 414
PUBMED: 38961288
DOI: doi:10.1038/s41586-024-07605-8
ISSN: 1476-4687
ASTM: NATUAS