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EMD-37210
Prefusion RSV F Bound to Lonafarnib and D25 Fab
EMD-37210
Single-particle3.17 Å
Deposition: 17/08/2023Map released: 19/06/2024
Last modified: 16/07/2025
Sample Organism:
Homo sapiens,
Human respiratory syncytial virus A (strain A2),
Enterobacteria phage T4
Sample: Prefusion RSV F Bound to Lonafarnib and D25 Fab
Fitted models: 8kg5
Deposition Authors: Yang Q, Xue B, Liu F
,
Peng W,
Chen X
Sample: Prefusion RSV F Bound to Lonafarnib and D25 Fab
Fitted models: 8kg5
Deposition Authors: Yang Q, Xue B, Liu F
,
Peng W,
Chen X
Farnesyltransferase inhibitor lonafarnib suppresses respiratory syncytial virus infection by blocking conformational change of fusion glycoprotein.
Yang Q,
Xue B,
Liu F ,
Lu Y,
Tang J,
Yan M,
Wu Q,
Chen R,
Zhou A,
Liu L,
Liu J,
Qu C,
Wu Q,
Fu M,
Zhong J,
Dong J,
Chen S,
Wang F ,
Zhou Y,
Zheng J,
Peng W,
Shang J ,
Chen X
(2024) Signal Transduct Target Ther , 9 , 144 - 144
,
Lu Y,
Tang J,
Yan M,
Wu Q,
Chen R,
Zhou A,
Liu L,
Liu J,
Qu C,
Wu Q,
Fu M,
Zhong J,
Dong J,
Chen S,
Wang F ,
Zhou Y,
Zheng J,
Peng W,
Shang J ,
Chen X
(2024) Signal Transduct Target Ther , 9 , 144 - 144
Grant Support: