EMD-37121
Structure of nucleosome complexed with one DEK molecule
EMD-37121
Single-particle3.2 Å
Deposition: 08/08/2023Map released: 12/03/2025
Last modified: 30/07/2025
Sample Organism:
Homo sapiens,
synthetic construct
Sample: DEK monomer bound to the nucleosome
Fitted models: 8kd1
Deposition Authors: Kujirai T
,
Echigoya K ,
Takizawa Y ,
Kurumizaka H
Sample: DEK monomer bound to the nucleosome
Fitted models: 8kd1
Deposition Authors: Kujirai T
,
Echigoya K ,
Takizawa Y ,
Kurumizaka H
Structural insights into how DEK nucleosome binding facilitates H3K27 trimethylation in chromatin.
Kujirai T ,
Echigoya K ,
Kishi Y ,
Saeki M,
Ito T,
Kato J,
Negishi L ,
Kimura H ,
Masumoto H,
Takizawa Y ,
Gotoh Y ,
Kurumizaka H
(2025) Nat Struct Mol Biol , 32 , 1183 - 1192
,
Echigoya K ,
Kishi Y ,
Saeki M,
Ito T,
Kato J,
Negishi L ,
Kimura H ,
Masumoto H,
Takizawa Y ,
Gotoh Y ,
Kurumizaka H
(2025) Nat Struct Mol Biol , 32 , 1183 - 1192
Grant Support:
- Japan Society for the Promotion of Science (JSPS): JP20H03201 (Japan)
- Japan Society for the Promotion of Science (JSPS): JP20H05690 (Japan)
- Japan Society for the Promotion of Science (JSPS): JP22K15033 (Japan)
- Japan Society for the Promotion of Science (JSPS): JP23H05475 (Japan)
- Japan Science and Technology: JPMJER1901 (Japan)
- Japan Agency for Medical Research and Development (AMED): JP22ama121009 (Japan)
- Japan Society for the Promotion of Science (JSPS): JP22K06098 (Japan)
- Japan Society for the Promotion of Science (JSPS): JP22KJ0871 (Japan)