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EMD-36905
SARS-CoV-2 BA.1 RBD with UT28-RD
EMD-36905
Single-particle3.41 Å
Deposition: 21/07/2023Map released: 27/12/2023
Last modified: 09/10/2024
Sample Organism:
Homo sapiens,
Severe acute respiratory syndrome coronavirus 2
Sample: SARS-CoV-2 BA.1 spike protein with UT28K-RD complex
Fitted models: 8k5g
Deposition Authors: Chen L, Kita S, Anraku Y
,
Maenaka K
Sample: SARS-CoV-2 BA.1 spike protein with UT28K-RD complex
Fitted models: 8k5g
Deposition Authors: Chen L, Kita S, Anraku Y
,
Maenaka K
Rational in silico design identifies two mutations that restore UT28K SARS-CoV-2 monoclonal antibody activity against Omicron BA.1.
Ozawa T
,
Ikeda Y,
Chen L,
Suzuki R,
Hoshino A,
Noguchi A,
Kita S,
Anraku Y
,
Igarashi E,
Saga Y,
Inasaki N,
Taminishi S,
Sasaki J,
Kirita Y,
Fukuhara H,
Maenaka K,
Hashiguchi T,
Fukuhara T,
Hirabayashi K,
Tani H,
Kishi H,
Niimi H
(2024) Structure , 32 , 263 - 272.e7
,
Ikeda Y,
Chen L,
Suzuki R,
Hoshino A,
Noguchi A,
Kita S,
Anraku Y
,
Igarashi E,
Saga Y,
Inasaki N,
Taminishi S,
Sasaki J,
Kirita Y,
Fukuhara H,
Maenaka K,
Hashiguchi T,
Fukuhara T,
Hirabayashi K,
Tani H,
Kishi H,
Niimi H
(2024) Structure , 32 , 263 - 272.e7
Grant Support:
- Japan Agency for Medical Research and Development (AMED): JP21am0101077 and JP22ama121010 (Japan)
- Japan Agency for Medical Research and Development (AMED): JP22ae0121018 (Japan)
- Japan Society for the Promotion of Science (JSPS): JP20K07624 and JP23H02776 (Japan)
- Japan Agency for Medical Research and Development (AMED): JP23fa627009 (Japan)
- Other government: JPMJCR20H8
