EMD-36890

Single-particle
2.9 Å
EMD-36890
3D View Gallery
Deposition: 20/07/2023
Map released: 06/11/2024
Last modified: 25/12/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-36890

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8k4s summary report (pdf.gz) Map-8k4s FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

CryoEM structure of Gq coupled MRGPRX4 with agonist DCA-3P

EMD-36890

Single-particle
2.9 Å
EMD-36890
3D View Gallery
Deposition: 20/07/2023
Map released: 06/11/2024
Last modified: 25/12/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Aequorea victoria, Mus musculus
Sample: Complex of MRGPRX4 with Gq and agonist DCA-3P
Fitted models: 8k4s

Deposition Authors: Yang J, Fan JP, Lei XG
Structure-guided discovery of bile acid derivatives for treating liver diseases without causing itch.
Yang J, Zhao T, Fan J, Zou H, Lan G, Guo F, Shi Y, Ke H, Yu H , Yue Z, Wang X, Bai Y, Li S, Liu Y, Wang X, Chen Y, Li Y, Lei X
(2024) Cell , 187 , 7164 - 7182.e18
PUBMED: 39476841
DOI: doi:10.1016/j.cell.2024.10.001
ISSN: 1097-4172