EMD-36890

Single-particle
2.9 Å
EMD-36890
3D View Gallery
Deposition: 20/07/2023
Map released: 06/11/2024
Last modified: 25/12/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-36890

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8k4s summary report (pdf.gz) Map-8k4s FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

CryoEM structure of Gq coupled MRGPRX4 with agonist DCA-3P

EMD-36890

Single-particle
2.9 Å
EMD-36890
3D View Gallery
Deposition: 20/07/2023
Map released: 06/11/2024
Last modified: 25/12/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Aequorea victoria, Mus musculus
Sample: Complex of MRGPRX4 with Gq and agonist DCA-3P
Fitted models: 8k4s

Deposition Authors: Yang J, Fan JP, Lei XG
Structure-guided discovery of bile acid derivatives for treating liver diseases without causing itch.
Yang J, Zhao T, Fan J, Zou H, Lan G, Guo F, Shi Y, Ke H, Yu H, Yue Z, Wang X, Bai Y, Li S, Liu Y, Wang X, Chen Y, Li Y, Lei X
(2024) Cell , 187 , 7164 - 7182.e18
PUBMED: 39476841
DOI: doi:10.1016/j.cell.2024.10.001
ISSN: 1097-4172