Electron Microscopy Data Bank

Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-36751

Single-particle
3.25 Å

3D View Gallery

Deposition: 06/07/2023
Map released: 27/09/2023
Last modified: 28/05/2025

Overview 3D View Sample Experiment Validation Additional data Links

EMD-36751

Download

Outward_facing SLC15A4 monomer

EMD-36751

Single-particle
3.25 Å
EMD-36751

3D View Gallery

Deposition: 06/07/2023
Map released: 27/09/2023
Last modified: 28/05/2025

Overview 3D View Sample Experiment Validation Additional data Links

Sample Organism: Homo sapiens, synthetic construct
Sample: endolysosomal transporter
Fitted models: 8jzr

Deposition Authors: Zhang SS, Chen XD, Xie M

Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling.

Chen X, Xie M, Zhang S, Monguio-Tortajada M , Yin J, Liu C, Zhang Y, Delacretaz M , Song M, Wang Y , Dong L, Ding Q , Zhou B, Tian X, Deng H, Xu L, Liu X, Yang Z, Chang Q , Na J , Zeng W , Superti-Furga G , Rebsamen M , Yang M
(2023) Nat Commun , 14 , 6627 - 6627

PUBMED: 37863913
DOI: doi:10.1038/s41467-023-42210-9
ISSN: 2041-1723

Grant Support:

National Natural Science Foundation of China (NSFC): 21532004, 31570733 (China)