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EMD-35994
Intermediate structure of mPIEZO1-S2472E
EMD-35994
Single-particle3.74 Å
Deposition: 24/04/2023Map released: 15/01/2025
Last modified: 05/03/2025
Sample Organism:
Mus musculus
Sample: S2472E-Intermediate Structure
Deposition Authors: Liu S
,
Yang X ,
Chen X ,
Li X ,
Xiao B
Sample: S2472E-Intermediate Structure
Deposition Authors: Liu S
,
Yang X ,
Chen X ,
Li X ,
Xiao B
An intermediate open structure reveals the gating transition of the mechanically activated PIEZO1 channel.
Liu S ,
Yang X ,
Chen X ,
Zhang X,
Jiang J ,
Yuan J,
Liu W,
Wang L,
Zhou H ,
Wu K,
Tian B,
Li X ,
Xiao B
(2025) Neuron , 113 , 590 - 604.e6
,
Yang X ,
Chen X ,
Zhang X,
Jiang J ,
Yuan J,
Liu W,
Wang L,
Zhou H ,
Wu K,
Tian B,
Li X ,
Xiao B
(2025) Neuron , 113 , 590 - 604.e6
Grant Support:
- Other government: 2016YFA0500402
- National Natural Science Foundation of China (NSFC): 31825014 (China)
- National Natural Science Foundation of China (NSFC): 32130049 (China)
- National Natural Science Foundation of China (NSFC): 32021002 (China)
- National Natural Science Foundation of China (NSFC): 31630090 (China)