EMD-35912
Cryo-EM structure of the AsCas12f-sgRNA-target DNA ternary complex
EMD-35912
Single-particle3.08 Å
Deposition: 12/04/2023Map released: 27/09/2023
Last modified: 09/10/2024
Sample Organism:
Acidibacillus sulfooxidans,
Mycolicibacterium mucogenicum
Sample: AsCas12f-sgRNA-target DNA
Fitted models: 8j12
Deposition Authors: Hino T
,
Omura NS,
Nakagawa R,
Togashi T ,
Takeda NS,
Hiramoto T,
Tasaka S,
Hirano H,
Tokuyama T,
Uosaki H ,
Ishiguro H,
Yamano H,
Ozaki Y,
Motooka D,
Mori H,
Kirita Y,
Kise Y,
Itoh Y ,
Matoba S,
Aburatani H,
Yachie N,
Siksnys V,
Ohmori T,
Hoshino A,
Nureki O
Sample: AsCas12f-sgRNA-target DNA
Fitted models: 8j12
Deposition Authors: Hino T
,
Omura NS,
Nakagawa R,
Togashi T ,
Takeda NS,
Hiramoto T,
Tasaka S,
Hirano H,
Tokuyama T,
Uosaki H ,
Ishiguro H,
Yamano H,
Ozaki Y,
Motooka D,
Mori H,
Kirita Y,
Kise Y,
Itoh Y ,
Matoba S,
Aburatani H,
Yachie N,
Siksnys V,
Ohmori T,
Hoshino A,
Nureki O
An AsCas12f-based compact genome-editing tool derived by deep mutational scanning and structural analysis.
Hino T ,
Omura SN,
Nakagawa R,
Togashi T ,
Takeda SN,
Hiramoto T,
Tasaka S,
Hirano H,
Tokuyama T,
Uosaki H ,
Ishiguro S,
Kagieva M,
Yamano H,
Ozaki Y,
Motooka D,
Mori H,
Kirita Y,
Kise Y,
Itoh Y ,
Matoba S,
Aburatani H,
Yachie N,
Karvelis T ,
Siksnys V,
Ohmori T,
Hoshino A,
Nureki O
(2023) Cell , 186 , 4920 - 4935.e23
,
Omura SN,
Nakagawa R,
Togashi T ,
Takeda SN,
Hiramoto T,
Tasaka S,
Hirano H,
Tokuyama T,
Uosaki H ,
Ishiguro S,
Kagieva M,
Yamano H,
Ozaki Y,
Motooka D,
Mori H,
Kirita Y,
Kise Y,
Itoh Y ,
Matoba S,
Aburatani H,
Yachie N,
Karvelis T ,
Siksnys V,
Ohmori T,
Hoshino A,
Nureki O
(2023) Cell , 186 , 4920 - 4935.e23
Grant Support: