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EMD-35832
Cryo-EM structure of the GPR34 receptor in complex with the antagonist YL-365
EMD-35832
Single-particle3.34 Å
Deposition: 06/04/2023Map released: 20/03/2024
Last modified: 02/07/2025
Sample Organism:
Homo sapiens
Sample: Cryo-EM structure of the GPR34 receptor in complex with the antagonist YL-365
Fitted models: 8iyx
Deposition Authors: Jia GW, Wang X
,
Zhang CB,
Dong HH,
Su ZM
Sample: Cryo-EM structure of the GPR34 receptor in complex with the antagonist YL-365
Fitted models: 8iyx
Deposition Authors: Jia GW, Wang X
,
Zhang CB,
Dong HH,
Su ZM
Cryo-EM structures of human GPR34 enable the identification of selective antagonists.
Xia A ,
Yong X ,
Zhang C ,
Lin G,
Jia G ,
Zhao C ,
Wang X ,
Hao Y ,
Wang Y,
Zhou P,
Yang X,
Deng Y,
Wu C,
Chen Y,
Zhu J,
Tang X,
Liu J,
Zhang S,
Zhang J,
Xu Z,
Hu Q,
Zhao J,
Yue Y,
Yan W,
Su Z ,
Wei Y,
Zhou R,
Dong H,
Shao Z ,
Yang S
(2023) PNAS , 120 , e2308435120 - e2308435120
,
Yong X ,
Zhang C ,
Lin G,
Jia G ,
Zhao C ,
Wang X ,
Hao Y ,
Wang Y,
Zhou P,
Yang X,
Deng Y,
Wu C,
Chen Y,
Zhu J,
Tang X,
Liu J,
Zhang S,
Zhang J,
Xu Z,
Hu Q,
Zhao J,
Yue Y,
Yan W,
Su Z ,
Wei Y,
Zhou R,
Dong H,
Shao Z ,
Yang S
(2023) PNAS , 120 , e2308435120 - e2308435120
Grant Support: