Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-35799

Single-particle
4.07 Å
EMD-35799 Deposition: 01/04/2023
Map released: 01/01/2025
Last modified: 25/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-35799

Curved structure of mPIEZO1-S2472E

EMD-35799

Single-particle
4.07 Å
EMD-35799 Deposition: 01/04/2023
Map released: 01/01/2025
Last modified: 25/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: S2472E-Curved Structure
Fitted models: 8ixn

Deposition Authors: Liu S, Yang X, Chen X, Li X, Xiao B
An intermediate open structure reveals the gating transition of the mechanically activated PIEZO1 channel.
Liu S, Yang X, Chen X, Zhang X, Jiang J , Yuan J, Liu W, Wang L, Zhou H , Wu K, Tian B, Li X, Xiao B
(2025) Neuron , 113 , 590
PUBMED: 39719701
DOI: doi:10.1016/j.neuron.2024.11.020
ISSN: 0896-6273
ASTM: NERNET