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EMD-35707
Cryo-EM structure of GIPR splice variant 2 (SV2) in complex with Gs protein
EMD-35707
Single-particle3.13 Å
Deposition: 22/03/2023Map released: 18/10/2023
Last modified: 23/07/2025
Sample Organism:
Homo sapiens,
Bos taurus,
Rattus norvegicus,
synthetic construct
Sample: Cryo-EM structure of a splice variant of the GIPR(SV2) in complex with Gs protein
Fitted models: 8itm
Deposition Authors: Zhao FH, Hang KN, Zhou QT, Shao LJ, Li H, Li WZ, Lin S, Dai AT, Cai XQ, Liu YY, Xu YN, Feng WB, Yang DH, Wang MW
Sample: Cryo-EM structure of a splice variant of the GIPR(SV2) in complex with Gs protein
Fitted models: 8itm
Deposition Authors: Zhao FH, Hang KN, Zhou QT, Shao LJ, Li H, Li WZ, Lin S, Dai AT, Cai XQ, Liu YY, Xu YN, Feng WB, Yang DH, Wang MW
Molecular basis of signal transduction mediated by the human GIPR splice variants.
Zhao F,
Hang K,
Zhou Q ,
Shao L,
Li H,
Li W,
Lin S,
Dai A,
Cai X,
Liu Y,
Xu Y,
Feng W ,
Yang D ,
Wang MW
(2023) PNAS , 120 , e2306145120 - e2306145120
,
Shao L,
Li H,
Li W,
Lin S,
Dai A,
Cai X,
Liu Y,
Xu Y,
Feng W ,
Yang D ,
Wang MW
(2023) PNAS , 120 , e2306145120 - e2306145120
Grant Support:
- National Natural Science Foundation of China (NSFC): 81872915 (China)
- National Natural Science Foundation of China (NSFC): 82073904 (China)
- National Natural Science Foundation of China (NSFC): 82121005 (China)
- National Natural Science Foundation of China (NSFC): 81973373 (China)
- National Natural Science Foundation of China (NSFC): 21704064 (China)
- National Natural Science Foundation of China (NSFC): 82204474 (China)