Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-35694

Single-particle
3.19 Å
EMD-35694 Deposition: 21/03/2023
Map released: 18/10/2023
Last modified: 25/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-35694

Cryo-EM structure of wild-type human tRNA Splicing Endonuclease Complex bound to pre-tRNA-ARG at 3.19 A resolution

EMD-35694

Single-particle
3.19 Å
EMD-35694 Deposition: 21/03/2023
Map released: 18/10/2023
Last modified: 25/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human pre-tRNA splicing complex TSEN with substrate RNA
Fitted models: 8iss

Deposition Authors: Sun Y , Zhang Y , Yuan L, Han Y
Recognition and cleavage mechanism of intron-containing pre-tRNA by human TSEN endonuclease complex.
Yuan L, Han Y , Zhao J , Zhang Y , Sun Y
(2023) Nat Commun , 14 , 6071 - 6071
PUBMED: 37770519
DOI: doi:10.1038/s41467-023-41845-y
ISSN: 2041-1723
Grant Support: