EMD-35627

Single-particle
3.2 Å
EMD-35627
3D View Gallery
Deposition: 13/03/2023
Map released: 20/03/2024
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-35627

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8iow summary report (pdf.gz) Map-8iow FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the sarilumab Fab/IL-6R complex

EMD-35627

Single-particle
3.2 Å
EMD-35627
3D View Gallery
Deposition: 13/03/2023
Map released: 20/03/2024
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: the sarilumab Fab/IL-6R complex
Fitted models: 8iow

Deposition Authors: She J , Chen L, Wang MX
Structural insights into IL-6 signaling inhibition by therapeutic antibodies.
Wang M, Chen L, He J, Xia W, Ye Z, She J
(2024) Cell Rep , 43 , 113819 - 113819
PUBMED: 38393945
DOI: doi:10.1016/j.celrep.2024.113819
ISSN: 2211-1247