Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-35616
Cryo-EM structure of the PG-901-bound human melanocortin receptor 5 (MC5R)-Gs complex
EMD-35616
Single-particle2.59 Å
Deposition: 10/03/2023Map released: 20/09/2023
Last modified: 06/11/2024
Sample Organism:
Homo sapiens,
Bos taurus,
synthetic construct
Sample: Cryo-EM structure of PG-901-bound human melanocortin receptor 5 in complex with G protein
Fitted models: 8iod
Deposition Authors: Feng WB, Zhou QT, Chen XY, Dai AT, Cai XQ, Liu X, Zhao FH, Chen Y, Ye CY, Xu YN, Cong ZT, Li H, Lin S, Yang DH, Wang MW
Sample: Cryo-EM structure of PG-901-bound human melanocortin receptor 5 in complex with G protein
Fitted models: 8iod
Deposition Authors: Feng WB, Zhou QT, Chen XY, Dai AT, Cai XQ, Liu X, Zhao FH, Chen Y, Ye CY, Xu YN, Cong ZT, Li H, Lin S, Yang DH, Wang MW
Structural insights into ligand recognition and subtype selectivity of the human melanocortin-3 and melanocortin-5 receptors.
Feng W,
Zhou Q
,
Chen X,
Dai A,
Cai X,
Liu X,
Zhao F,
Chen Y,
Ye C,
Xu Y,
Cong Z,
Li H,
Lin S,
Yang D
,
Wang MW
(2023) Cell Discov , 9 , 81
,
Chen X,
Dai A,
Cai X,
Liu X,
Zhao F,
Chen Y,
Ye C,
Xu Y,
Cong Z,
Li H,
Lin S,
Yang D
,
Wang MW
(2023) Cell Discov , 9 , 81
Grant Support:
- National Natural Science Foundation of China (NSFC): 81872915 (China)
- National Natural Science Foundation of China (NSFC): 82073904 (China)
- National Natural Science Foundation of China (NSFC): 82121005 (China)
- National Natural Science Foundation of China (NSFC): 81973373 (China)
- National Natural Science Foundation of China (NSFC): 21704064 (China)
- Other government: 2018YFA0507000
- Other government: 2018ZX09735-001
- Other government: 2018ZX09711002-002-005
- Other government: STI2030-Major project 2021ZD0203400
- Other government: ZDKJ2021028
- Other government: 21JC1401600
