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EMD-35615
Cryo-EM structure of the gamma-MSH-bound human melanocortin receptor 3 (MC3R)-Gs complex
EMD-35615
Single-particle2.86 Å
Deposition: 10/03/2023Map released: 20/09/2023
Last modified: 06/11/2024
Sample Organism:
Homo sapiens,
Bos taurus,
synthetic construct
Sample: Cryo-EM structure of gamma-MSH-bound human melanocortin receptor 3 in complex with G protein
Fitted models: 8ioc
Deposition Authors: Feng WB, Zhou QT, Chen XY, Dai AT, Cai XQ, Liu X, Zhao FH, Chen Y, Ye CY, Xu YN, Cong ZT, Li H, Lin S
Sample: Cryo-EM structure of gamma-MSH-bound human melanocortin receptor 3 in complex with G protein
Fitted models: 8ioc
Deposition Authors: Feng WB, Zhou QT, Chen XY, Dai AT, Cai XQ, Liu X, Zhao FH, Chen Y, Ye CY, Xu YN, Cong ZT, Li H, Lin S
Structural insights into ligand recognition and subtype selectivity of the human melanocortin-3 and melanocortin-5 receptors.
Feng W,
Zhou Q
,
Chen X,
Dai A,
Cai X,
Liu X,
Zhao F,
Chen Y,
Ye C,
Xu Y,
Cong Z,
Li H,
Lin S,
Yang D
,
Wang MW
(2023) Cell Discov , 9 , 81
,
Chen X,
Dai A,
Cai X,
Liu X,
Zhao F,
Chen Y,
Ye C,
Xu Y,
Cong Z,
Li H,
Lin S,
Yang D
,
Wang MW
(2023) Cell Discov , 9 , 81
Grant Support:
- National Natural Science Foundation of China (NSFC): 81872915 (China)
- National Natural Science Foundation of China (NSFC): 82073904 (China)
- National Natural Science Foundation of China (NSFC): 82121005 (China)
- National Natural Science Foundation of China (NSFC): 81973373 (China)
- National Natural Science Foundation of China (NSFC): 21704064 (China)
- Other government: 2018YFA0507000
- Other government: 2018ZX09735-001
- Other government: 2018ZX09711002-002-005
- Other government: STI2030-Major project 2021ZD0203400
- Other government: ZDKJ2021028
- Other government: 21JC1401600
