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EMD-35547

Single-particle
3.19 Å
EMD-35547
3D View Gallery
Deposition: 04/03/2023
Map released: 06/09/2023
Last modified: 06/09/2023
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-35547
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3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8ilv summary report (pdf.gz) Map and 8ilv FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of PI3Kalpha in complex with compound 18

EMD-35547

Single-particle
3.19 Å
EMD-35547
3D View Gallery
Deposition: 04/03/2023
Map released: 06/09/2023
Last modified: 06/09/2023
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human PI3Kalpha in complex with compound 18
Fitted models: 8ilv

Deposition Authors: Zhou Q , Liu X, Neri D, Li W, Favalli N, Bassi G, Yang S, Yang D , Vogt PK , Wang M-W
Structural insights into the interaction of three Y-shaped ligands with PI3K alpha.
Zhou Q , Liu X, Neri D, Li W, Favalli N, Bassi G, Yang S, Yang D , Vogt PK , Wang MW
(2023) PNAS , 120 , e2304071120 - e2304071120
PUBMED: 37585458
DOI: doi:10.1073/pnas.2304071120
ISSN: 1091-6490
ASTM: PNASA6