EMD-35545

Single-particle
3.1 Å
EMD-35545
3D View Gallery
Deposition: 04/03/2023
Map released: 13/09/2023
Last modified: 13/09/2023
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-35545

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8ils summary report (pdf.gz) Map-8ils FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of PI3Kalpha in complex with compound 17

EMD-35545

Single-particle
3.1 Å
EMD-35545
3D View Gallery
Deposition: 04/03/2023
Map released: 13/09/2023
Last modified: 13/09/2023
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human PI3Kalpha in complex with compound 17
Fitted models: 8ils

Deposition Authors: Zhou Q , Liu X, Neri D, Li W, Favalli N, Bassi G, Yang S, Yang D , Vogt PK , Wang M-W
Structural insights into the interaction of three Y-shaped ligands with PI3K alpha.
Zhou Q , Liu X, Neri D, Li W, Favalli N, Bassi G, Yang S, Yang D , Vogt PK , Wang MW
(2023) PNAS , 120 , e2304071120 - e2304071120
PUBMED: 37585458
DOI: doi:10.1073/pnas.2304071120
ISSN: 1091-6490
ASTM: PNASA6