EMD-35487

Single-particle
3.4 Å
EMD-35487
3D View Gallery
Deposition: 27/02/2023
Map released: 17/01/2024
Last modified: 10/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-35487

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8ijk summary report (pdf.gz) Map-8ijk FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

human KCNQ2-CaM-Ebio1 complex in the presence of PIP2

EMD-35487

Single-particle
3.4 Å
EMD-35487
3D View Gallery
Deposition: 27/02/2023
Map released: 17/01/2024
Last modified: 10/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: human KCNQ2-CaM-Ebio1 complex in the presence of PIP2
Fitted models: 8ijk

Deposition Authors: Ma D , Guo J
A small-molecule activation mechanism that directly opens the KCNQ2 channel.
Zhang S, Ma D , Wang K, Li Y, Yang Z, Li X, Li J, He J, Mei L, Ye Y, Chen Z, Shen J, Hou P, Guo J , Zhang Q , Yang H
(2024) Nat Chem Biol , 20 , 847 - 856
PUBMED: 38167918
DOI: doi:10.1038/s41589-023-01515-y
ISSN: 1552-4469