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EMD-35157

Single-particle
2.85 Å
EMD-35157
3D View Gallery
Deposition: 18/01/2023
Map released: 03/07/2024
Last modified: 25/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-35157
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8i3v summary report (pdf.gz) Map and 8i3v FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of human norepinephrine transporter NET in the presence of the antidepressant escitalopram in an inward-open state at resolution of 2.85 angstrom.

EMD-35157

Single-particle
2.85 Å
EMD-35157
3D View Gallery
Deposition: 18/01/2023
Map released: 03/07/2024
Last modified: 25/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: NET
Fitted models: 8i3v

Deposition Authors: Tan J , Xiao Y , Kong F , Lei J , Yuan Y , Yan C
Molecular basis of human noradrenaline transporter reuptake and inhibition.
Tan J , Xiao Y , Kong F , Zhang X , Xu H, Zhu A , Liu Y, Lei J , Tian B , Yuan Y , Yan C
(2024) Nature , 632 , 921 - 929
PUBMED: 39048818
DOI: doi:10.1038/s41586-024-07719-z
ISSN: 1476-4687
ASTM: NATUAS
Grant Support: