EMD-34919

Single-particle
3.1 Å
EMD-34919
3D View Gallery
Deposition: 08/12/2022
Map released: 19/07/2023
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-34919

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8hnv summary report (pdf.gz) Map-8hnv FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

CryoEM structure of HpaCas9-sgRNA-dsDNA in the presence of AcrIIC4

EMD-34919

Single-particle
3.1 Å
EMD-34919
3D View Gallery
Deposition: 08/12/2022
Map released: 19/07/2023
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Haemophilus parainfluenzae, synthetic construct
Sample: Complex of HpaCas9-sgRNA-DNA in the presence of AcrIIC4
Fitted models: 8hnv

Deposition Authors: Sun W , Cheng Z , Wang J, Yang X, Wang Y
AcrIIC4 inhibits type II-C Cas9 by preventing R-loop formation.
Sun W , Cheng Z , Wang J, Yang J , Li X , Wang J, Chen M, Yang X, Sheng G, Lou J, Wang Y
(2023) PNAS , 120 , e2303675120 - e2303675120
PUBMED: 37494395
DOI: doi:10.1073/pnas.2303675120
ISSN: 1091-6490
ASTM: PNASA6