Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-34892

Single-particle
3.3 Å
EMD-34892
3D View Gallery
Deposition: 02/12/2022
Map released: 24/04/2024
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-34892
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8hmb summary report (pdf.gz) Map and 8hmb FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of human high-voltage activated L-type calcium channel CaV1.2 in complex with benidipine (BEN)

EMD-34892

Single-particle
3.3 Å
EMD-34892
3D View Gallery
Deposition: 02/12/2022
Map released: 24/04/2024
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: CaV3.3
Fitted models: 8hmb

Deposition Authors: Wei Y , Yu Z, Zhao Y
Structural bases of inhibitory mechanism of Ca V 1.2 channel inhibitors.
Wei Y , Yu Z, Wang L, Li X, Li N, Bai Q, Wang Y, Li R, Meng Y , Xu H, Wang X, Dong Y , Huang Z , Zhang XC , Zhao Y
(2024) Nat Commun , 15 , 2772 - 2772
PUBMED: 38555290
DOI: doi:10.1038/s41467-024-47116-8
ISSN: 2041-1723
Grant Support: