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EMD-34804
Cryo-EM structure of the Cas12m2-crRNA-target DNA ternary complex intermediate state
EMD-34804
Single-particle3.08 Å
Deposition: 16/11/2022Map released: 12/04/2023
Last modified: 22/05/2024
Sample Organism:
Mycolicibacterium mucogenicum
Sample: Cas12m2-crRNA-target DNA
Fitted models: 8hhm
Deposition Authors: Omura NS, Nakagawa R, Wu YW, Sudfeld C, Warren VR, Hirano H, Kusakizako T
,
Kise Y,
Lebbink HGJ,
Itoh Y ,
Oost VDJ,
Nureki O
Sample: Cas12m2-crRNA-target DNA
Fitted models: 8hhm
Deposition Authors: Omura NS, Nakagawa R, Wu YW, Sudfeld C, Warren VR, Hirano H, Kusakizako T
,
Kise Y,
Lebbink HGJ,
Itoh Y ,
Oost VDJ,
Nureki O
Mechanistic and evolutionary insights into a type V-M CRISPR-Cas effector enzyme.
Omura SN,
Nakagawa R,
Sudfeld C,
Villegas Warren R ,
Wu WY ,
Hirano H,
Laffeber C,
Kusakizako T ,
Kise Y,
Lebbink JHG ,
Itoh Y ,
van der Oost J ,
Nureki O
(2023) Nat Struct Mol Biol , 30 , 1172 - 1182
,
Wu WY ,
Hirano H,
Laffeber C,
Kusakizako T ,
Kise Y,
Lebbink JHG ,
Itoh Y ,
van der Oost J ,
Nureki O
(2023) Nat Struct Mol Biol , 30 , 1172 - 1182
Grant Support: