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EMD-34721

Single-particle
2.5 Å
EMD-34721
3D View Gallery
Deposition: 10/11/2022
Map released: 15/05/2024
Last modified: 16/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-34721
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8hfi summary report (pdf.gz) Map and 8hfi FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of human norepinephrine transporter NET in the presence of the antidepressant desipramine in an inward-open state at resolution of 2.5 angstrom.

EMD-34721

Single-particle
2.5 Å
EMD-34721
3D View Gallery
Deposition: 10/11/2022
Map released: 15/05/2024
Last modified: 16/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: NET
Fitted models: 8hfi

Deposition Authors: Tan J , Xiao Y , Kong F , Lei J , Yuan Y , Yan C , Yan C
Molecular basis of human noradrenaline transporter reuptake and inhibition.
Tan J , Xiao Y , Kong F , Zhang X , Xu H, Zhu A , Liu Y, Lei J , Tian B , Yuan Y , Yan C
(2024) Nature , 632 , 921 - 929
PUBMED: 39048818
DOI: doi:10.1038/s41586-024-07719-z
ISSN: 1476-4687
ASTM: NATUAS