EMD-3426

Single-particle
21.0 Å
EMD-3426
3D View Gallery
Deposition: 08/05/2016
Map released: 22/06/2016
Last modified: 22/06/2016
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-3426

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Electron cryo-microscopy of human P-glycoprotein: ATP bound state - open conformation

EMD-3426

Single-particle
21.0 Å
EMD-3426
3D View Gallery
Deposition: 08/05/2016
Map released: 22/06/2016
Last modified: 22/06/2016
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: human P-glycoprotein (E556Q/E1201Q) in an ATP-binding state, bound to UIC2 Fab

Deposition Authors: Frank GA , Shukla S, Rao P, Borgnia MJ , Bartesaghi A, Merk A, Mobin A, Esser L, Earl LA, Gottesman MM, Xia D, Ambudkar SV, Subramaniam S
Conformational landscape of human P-glycoprotein (ABCB1) during its catalytic cycle
Frank GA , Shukla S, Rao P, Borgnia MJ , Bartesaghi A, Merk A, Mobin A, Esser L, Earl LA, Gottesman MM, Xia D, Ambudkar SV, Subramaniam S
(2016) MOL.PHARMACOL. , 90 , 35 - 41