EMD-34245

Single-particle
3.47 Å
EMD-34245
3D View Gallery
Deposition: 07/09/2022
Map released: 28/12/2022
Last modified: 19/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-34245

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8gt6 summary report (pdf.gz) Map-8gt6 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

human STING With agonist HB3089

EMD-34245

Single-particle
3.47 Å
EMD-34245
3D View Gallery
Deposition: 07/09/2022
Map released: 28/12/2022
Last modified: 19/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human STING with agonist HB3089
Fitted models: 8gt6

Deposition Authors: Wang Z, Yu X
Structural insights into a shared mechanism of human STING activation by a potent agonist and an autoimmune disease-associated mutation.
Xie Z , Wang Z, Fan F, Zhou J, Hu Z, Wang Q, Wang X, Zeng Q, Zhang Y, Qiu J, Zhou X, Xu H, Bai H, Zhan Z, Ding J , Zhang H, Duan W, Yu X , Geng M
(2022) Cell Discov , 8 , 133 - 133
PUBMED: 36513640
DOI: doi:10.1038/s41421-022-00481-4
ISSN: 2056-5968