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EMD-34244
Structure of STING SAVI-related mutant V147L
EMD-34244
Single-particle3.65 Å
Deposition: 07/09/2022Map released: 28/12/2022
Last modified: 19/06/2024
Sample Organism:
Homo sapiens
Sample: STING SAVI-relatated mutant V147L
Fitted models: 8gsz
Deposition Authors: Wang Z, Yu X
Sample: STING SAVI-relatated mutant V147L
Fitted models: 8gsz
Deposition Authors: Wang Z, Yu X
Structural insights into a shared mechanism of human STING activation by a potent agonist and an autoimmune disease-associated mutation.
Xie Z ,
Wang Z,
Fan F,
Zhou J,
Hu Z,
Wang Q,
Wang X,
Zeng Q,
Zhang Y,
Qiu J,
Zhou X,
Xu H,
Bai H,
Zhan Z,
Ding J ,
Zhang H,
Duan W,
Yu X ,
Geng M
(2022) Cell Discov , 8 , 133 - 133
,
Wang Z,
Fan F,
Zhou J,
Hu Z,
Wang Q,
Wang X,
Zeng Q,
Zhang Y,
Qiu J,
Zhou X,
Xu H,
Bai H,
Zhan Z,
Ding J ,
Zhang H,
Duan W,
Yu X ,
Geng M
(2022) Cell Discov , 8 , 133 - 133
Grant Support:
- Other government: TZX022021007 (China)
- National Natural Science Foundation of China (NSFC): 81821005 (China)
- Other government: LG202103-02-08 (China)
- Other government: 2020CXJQ02 (China)
- National Natural Science Foundation of China (NSFC): 32000896 (China)
- Other government: 2020M681427 (China)