EMD-34202

Single-particle
3.5 Å
EMD-34202
3D View Gallery
Deposition: 30/08/2022
Map released: 05/07/2023
Last modified: 08/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-34202

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8gqu summary report (pdf.gz) Map-8gqu FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

AK-42 inhibitor binding human ClC-2 TMD

EMD-34202

Single-particle
3.5 Å
EMD-34202
3D View Gallery
Deposition: 30/08/2022
Map released: 05/07/2023
Last modified: 08/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: AK-42 inhibitor binding human ClC-2 TMD 3.5A
Fitted models: 8gqu

Deposition Authors: Wang L
Cryo-EM structures of ClC-2 chloride channel reveal the blocking mechanism of its specific inhibitor AK-42.
Ma T , Wang L , Chai A , Liu C, Cui W , Yuan S , Wing Ngor Au S, Sun L, Zhang X, Zhang Z, Lu J, Gao Y, Wang P , Li Z , Liang Y , Vogel H , Wang YT , Wang D , Yan K , Zhang H
(2023) Nat Commun , 14 , 3424 - 3424
PUBMED: 37296152
DOI: doi:10.1038/s41467-023-39218-6
ISSN: 2041-1723