EMD-34091

Single-particle
2.77 Å
EMD-34091
3D View Gallery
Deposition: 15/08/2022
Map released: 15/11/2023
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-34091

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7ytp summary report (pdf.gz) Map-7ytp FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

TLR7 in complex with an inhibitor

EMD-34091

Single-particle
2.77 Å
EMD-34091
3D View Gallery
Deposition: 15/08/2022
Map released: 15/11/2023
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Macaca mulatta
Sample: TLR7 in complex with an inhibitor
Fitted models: 7ytp

Deposition Authors: Zhang Z, Ohto U, Shimizu T
A novel Toll-like receptor 7/8-specific antagonist E6742 ameliorates clinically relevant disease parameters in murine models of lupus.
Ishizaka ST, Hawkins L, Chen Q, Tago F, Yagi T, Sakaniwa K, Zhang Z, Shimizu T, Shirato M
(2023) Eur.J.Pharmacol. , 957 , 175962 - 175962
PUBMED: 37544422
DOI: doi:10.1016/j.ejphar.2023.175962
ISSN: 0014-2999
Grant Support: