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EMD-34022
Cryo-EM structure of human topoisomerase II beta in complex with DNA and etoposide
EMD-34022
Single-particle3.9 Å
Deposition: 05/08/2022Map released: 03/01/2024
Last modified: 25/06/2025
Sample Organism:
Homo sapiens
Sample: Ternary complex of human topoisomerase II beta with DNA and etoposide
Fitted models: 7yq8
Deposition Authors: Naganuma M, Ehara H
,
Kim D,
Nakagawa R ,
Cong A ,
Bu H,
Jeong J,
Jang J,
Schellenberg MJ ,
Bunch H ,
Sekine S
Sample: Ternary complex of human topoisomerase II beta with DNA and etoposide
Fitted models: 7yq8
Deposition Authors: Naganuma M, Ehara H
,
Kim D,
Nakagawa R ,
Cong A ,
Bu H,
Jeong J,
Jang J,
Schellenberg MJ ,
Bunch H ,
Sekine S
ERK2-topoisomerase II regulatory axis is important for gene activation in immediate early genes.
Bunch H ,
Kim D,
Naganuma M,
Nakagawa R ,
Cong A ,
Jeong J,
Ehara H ,
Vu H,
Chang JH,
Schellenberg MJ ,
Sekine SI
(2023) Nat Commun , 14 , 8341 - 8341
,
Kim D,
Naganuma M,
Nakagawa R ,
Cong A ,
Jeong J,
Ehara H ,
Vu H,
Chang JH,
Schellenberg MJ ,
Sekine SI
(2023) Nat Commun , 14 , 8341 - 8341
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