Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-33939

Single-particle
3.51 Å
EMD-33939
3D View Gallery
Deposition: 29/07/2022
Map released: 10/08/2022
Last modified: 10/08/2022
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-33939
Download
3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7vmp summary report (pdf.gz) Map and 7vmp FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of recombinant RyR2 (Ca2+ dataset, class 2, open state)

EMD-33939

Single-particle
3.51 Å
EMD-33939
3D View Gallery
Deposition: 29/07/2022
Map released: 10/08/2022
Last modified: 10/08/2022
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, Homo sapiens
Sample: Recombinant RyR2 in the presence of Ca2+
Fitted models: 7vmp

Deposition Authors: Kobayashi T , Tsutsumi A , Kurebayashi N , Kodama M, Kikkawa M , Murayama T , Ogawa H
Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.
Kobayashi T , Tsutsumi A , Kurebayashi N , Saito K, Kodama M, Sakurai T , Kikkawa M , Murayama T , Ogawa H
(2022) Nat Commun , 13 , 2821 - 2821
PUBMED: 35595836
DOI: doi:10.1038/s41467-022-30429-x
ISSN: 2041-1723