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EMD-33889
Cryo-EM structure of the DC591053-bound human relaxin family peptide receptor 4 (RXFP4)-Gi complex
EMD-33889
Single-particle2.75 Å
Deposition: 21/07/2022Map released: 01/03/2023
Last modified: 06/11/2024
Sample Organism:
Homo sapiens,
Bos taurus,
synthetic construct
Sample: Cryo-EM structure of the human relaxin family peptide receptor 4 in complex with DC591053 and G protein
Fitted models: 7yk7
Deposition Authors: Chen Y, Zhou QT, Wang J, Xu YW, Wang Y, Yan JH, Wang YB, Zhu Q, Zhao FH, Li CH, Chen CW, Cai XQ, Bathgate RAD
,
Shen C,
Xu HE ,
Yang DH,
Liu H ,
Wang MW
Sample: Cryo-EM structure of the human relaxin family peptide receptor 4 in complex with DC591053 and G protein
Fitted models: 7yk7
Deposition Authors: Chen Y, Zhou QT, Wang J, Xu YW, Wang Y, Yan JH, Wang YB, Zhu Q, Zhao FH, Li CH, Chen CW, Cai XQ, Bathgate RAD
,
Shen C,
Xu HE ,
Yang DH,
Liu H ,
Wang MW
Ligand recognition mechanism of the human relaxin family peptide receptor 4 (RXFP4).
Chen Y,
Zhou Q,
Wang J,
Xu Y ,
Wang Y,
Yan J,
Wang Y,
Zhu Q,
Zhao F,
Li C,
Chen CW,
Cai X,
Bathgate RAD ,
Shen C,
Eric Xu H,
Yang D ,
Liu H ,
Wang MW
(2023) Nat Commun , 14 , 492 - 492
,
Wang Y,
Yan J,
Wang Y,
Zhu Q,
Zhao F,
Li C,
Chen CW,
Cai X,
Bathgate RAD ,
Shen C,
Eric Xu H,
Yang D ,
Liu H ,
Wang MW
(2023) Nat Commun , 14 , 492 - 492
Grant Support:
- National Natural Science Foundation of China (NSFC): 81872915 (China)
- National Natural Science Foundation of China (NSFC): 82073904 (China)
- National Natural Science Foundation of China (NSFC): 82120105 (China)
- National Natural Science Foundation of China (NSFC): 81973373 (China)
- National Natural Science Foundation of China (NSFC): 82130105 (China)
- National Natural Science Foundation of China (NSFC): 21704064 (China)
- Other government: 2021ZD0203400
- Other government: 2018YFA0507000
- Other government: ZDKJ2021028
- Other government: 21JC1401600
- Other government: 1135837