EMD-33698

Single-particle
3.1 Å
EMD-33698 Deposition: 26/06/2022
Map released: 21/09/2022
Last modified: 21/09/2022
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-33698

Cryo-EM structure of hACE2-bound SARS-CoV-2 Omicron spike protein with L371S, P373S and F375S mutations (S-6P-RRAR)

EMD-33698

Single-particle
3.1 Å
EMD-33698 Deposition: 26/06/2022
Map released: 21/09/2022
Last modified: 21/09/2022
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2, Homo sapiens
Sample: Cryo-EM structure of hACE2-bound SARS-CoV-2 Omicron spike protein with L371S, P373S and F375S mutations (local refinement)
Fitted models: 7ya0

Deposition Authors: Zhao ZN, Xie YF, Qi JX, Gao GF
Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape.
Zhao Z , Zhou J, Tian M, Huang M, Liu S, Xie Y , Han P, Bai C, Han P, Zheng A, Fu L, Gao Y, Peng Q, Li Y, Chai Y, Zhang Z, Zhao X , Song H , Qi J , Wang Q , Wang P , Gao GF
(2022) Nat Commun , 13 , 4958 - 4958
PUBMED: 36002453
DOI: doi:10.1038/s41467-022-32665-7
ISSN: 2041-1723