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EMD-33651
SARS-CoV-2 spike glycoprotein trimer complexed with Fab fragment of anti-RBD antibody E7 (focused refinement on Fab-RBD interface)
EMD-33651
Single-particle4.03 Å
Deposition: 21/06/2022Map released: 02/08/2023
Last modified: 30/10/2024
Sample Organism:
Homo sapiens
Sample: SARS-CoV-2 spike glycoprotein trimer complexed with Fab fragment of anti-RBD antibody E7
Fitted models: 7y72
Deposition Authors: Chia WN
,
Tan CW ,
Tan AWK ,
Young B ,
Starr TN ,
Lopez E ,
Fibriansah G ,
Barr J ,
Cheng S ,
Yeoh AYY,
Yap WC ,
Lim BL,
Ng TS ,
Sia WR ,
Zhu F ,
Chen S ,
Zhang J ,
Greaney AJ ,
Chen M ,
Au GG ,
Paradkar P,
Peiris M ,
Chung AW ,
Bloom JD ,
Lye D ,
Lok SM ,
Wang LF
Sample: SARS-CoV-2 spike glycoprotein trimer complexed with Fab fragment of anti-RBD antibody E7
Fitted models: 7y72
Deposition Authors: Chia WN
,
Tan CW ,
Tan AWK ,
Young B ,
Starr TN ,
Lopez E ,
Fibriansah G ,
Barr J ,
Cheng S ,
Yeoh AYY,
Yap WC ,
Lim BL,
Ng TS ,
Sia WR ,
Zhu F ,
Chen S ,
Zhang J ,
Greaney AJ ,
Chen M ,
Au GG ,
Paradkar P,
Peiris M ,
Chung AW ,
Bloom JD ,
Lye D ,
Lok SM ,
Wang LF
Potent pan huACE2-dependent sarbecovirus neutralizing monoclonal antibodies isolated from a BNT162b2-vaccinated SARS survivor.
Chia WN ,
Tan CW ,
Tan AWK ,
Young B ,
Starr TN ,
Lopez E ,
Fibriansah G ,
Barr J ,
Cheng S ,
Yeoh AY,
Yap WC ,
Lim BL,
Ng TS ,
Sia WR ,
Zhu F ,
Chen S ,
Zhang J ,
Kwek MSS ,
Greaney AJ ,
Chen M ,
Au GG ,
Paradkar PN ,
Peiris M ,
Chung AW ,
Bloom JD ,
Lye D ,
Lok S,
Wang LF
(2023) Sci Adv , 9 , eade3470 - eade3470
,
Tan CW ,
Tan AWK ,
Young B ,
Starr TN ,
Lopez E ,
Fibriansah G ,
Barr J ,
Cheng S ,
Yeoh AY,
Yap WC ,
Lim BL,
Ng TS ,
Sia WR ,
Zhu F ,
Chen S ,
Zhang J ,
Kwek MSS ,
Greaney AJ ,
Chen M ,
Au GG ,
Paradkar PN ,
Peiris M ,
Chung AW ,
Bloom JD ,
Lye D ,
Lok S,
Wang LF
(2023) Sci Adv , 9 , eade3470 - eade3470
Grant Support:
- National Research Foundation (NRF, Singapore): NRF2016NRF-NSFC002-013 (Singapore)
- Other government: STPRG-FY19-001 (Singapore)
- Other government: COVID19RF-003 (Singapore)
- Other government: COVID19RF-060 (Singapore)
- Other government: MOH-000535/MOH-OFYIRG19nov-0002 (Singapore)
- Other government: OFLCG19May-0034 (Singapore)
- National Health and Medical Research Council (NHMRC, Australia): GNT 2008092 (Australia)
- Damon Runyon Cancer Research Foundation: (United States)