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EMD-33628
CryoEM structure of PS2-containing gamma-secretase treated with MRK-560
EMD-33628
Single-particle3.0 Å
Deposition: 17/06/2022Map released: 02/11/2022
Last modified: 18/06/2025
Sample Organism:
Homo sapiens
Sample: PS2-containing gamma-secretase complex treated with MRK-560
Fitted models: 7y5x
Deposition Authors: Guo X
,
Wang Y ,
Zhou J,
Jin C,
Wang J,
Jia B ,
Jing D,
Yan C,
Lei J ,
Zhou R ,
Shi Y
Sample: PS2-containing gamma-secretase complex treated with MRK-560
Fitted models: 7y5x
Deposition Authors: Guo X
,
Wang Y ,
Zhou J,
Jin C,
Wang J,
Jia B ,
Jing D,
Yan C,
Lei J ,
Zhou R ,
Shi Y
Molecular basis for isoform-selective inhibition of presenilin-1 by MRK-560.
Guo X ,
Wang Y ,
Zhou J,
Jin C,
Wang J,
Jia B ,
Jing D,
Yan C,
Lei J ,
Zhou R ,
Shi Y
(2022) Nat Commun , 13 , 6299 - 6299
,
Wang Y ,
Zhou J,
Jin C,
Wang J,
Jia B ,
Jing D,
Yan C,
Lei J ,
Zhou R ,
Shi Y
(2022) Nat Commun , 13 , 6299 - 6299
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