Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-33489

Single-particle
3.04 Å
EMD-33489
3D View Gallery
Deposition: 26/05/2022
Map released: 08/03/2023
Last modified: 03/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-33489
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7xw2 summary report (pdf.gz) Map and 7xw2 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of human DICER-pre-miRNA in a dicing state

EMD-33489

Single-particle
3.04 Å
EMD-33489
3D View Gallery
Deposition: 26/05/2022
Map released: 08/03/2023
Last modified: 03/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Protein-RNA complex of human DICER with pre-miRNA
Fitted models: 7xw2

Deposition Authors: Lee H , Roh S-H
Structure of the human DICER-pre-miRNA complex in a dicing state.
Lee YY , Lee H , Kim H , Kim VN , Roh SH
(2023) Nature , 615 , 331 - 338
PUBMED: 36813958
DOI: doi:10.1038/s41586-023-05723-3
ISSN: 1476-4687
ASTM: NATUAS
Grant Support: