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EMD-33445

Single-particle
3.3 Å
EMD-33445 Deposition: 16/05/2022
Map released: 27/07/2022
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-33445

Serotonin 6 (5-HT6) receptor-Gs-Nb35 complex

EMD-33445

Single-particle
3.3 Å
EMD-33445 Deposition: 16/05/2022
Map released: 27/07/2022
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: Serotonin 6 (5-HT6) receptor-Gs-Nb35 complex
Fitted models: 7xtb

Deposition Authors: Huang S, Xu P, Shen DD, Simon IA , Mao C, Tan Y, Zhang H, Harpsoe K , Li H, Zhang Y, You C, Yu X, Jiang Y, Zhang Y, Gloriam DE , Xu HE
GPCRs steer G i and G s selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors.
Huang S, Xu P, Shen DD, Simon IA , Mao C, Tan Y, Zhang H, Harpsoe K , Li H, Zhang Y, You C, Yu X, Jiang Y, Zhang Y, Gloriam DE , Xu HE
(2022) Mol Cell , 82 , 2681 - 2695.e6
PUBMED: 35714614
DOI: doi:10.1016/j.molcel.2022.05.031
ISSN: 1097-2765
ASTM: MOCEFL