Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-33416

Single-particle
3.88 Å
EMD-33416
3D View Gallery
Deposition: 11/05/2022
Map released: 05/10/2022
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-33416
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7xrp summary report (pdf.gz) Map and 7xrp FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of SARS-CoV-2 spike protein in complex with nanobody C5G2 (localized refinement)

EMD-33416

Single-particle
3.88 Å
EMD-33416
3D View Gallery
Deposition: 11/05/2022
Map released: 05/10/2022
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2, Camelus dromedarius
Sample: Cryo-EM structure of SARS-CoV-2 spike protein in complex with nanobody C5G2 (local refinement)
Fitted models: 7xrp

Deposition Authors: Liu L, Sun H, Jiang Y, Liu X, Zhao D, Zheng Q , Li S, Xia N
A potent synthetic nanobody with broad-spectrum activity neutralizes SARS-CoV-2 virus and the Omicron variant BA.1 through a unique binding mode.
Zhao D, Liu L, Liu X, Zhang J, Yin Y, Luan L, Jiang D, Yang X, Li L, Xiong H, Xing D, Zheng Q , Xia N, Tao Y, Li S, Huang H
(2022) J Nanobiotechnology , 20 , 411 - 411
PUBMED: 36109732
DOI: doi:10.1186/s12951-022-01619-y
ISSN: 1477-3155
Grant Support: