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EMD-33398
Hemichannel-focused structure of C-terminal truncated connexin43/Cx43/GJA1 gap junction intercellular channel in POPE nanodiscs (PLN conformation)
EMD-33398
Single-particle4.0 Å
Deposition: 07/05/2022Map released: 25/01/2023
Last modified: 13/11/2024
Sample Organism:
Homo sapiens
Sample: Dodecameric complex of C-terminal deletion mutant of human Cx43/GJA1 (Cx43-M257) in lipid nanodiscs (POPE)
Fitted models: 7xqj
Deposition Authors: Lee HJ
,
Cha HJ
,
Jeong H
,
Lee SN
,
Lee CW,
Woo JS
Sample: Dodecameric complex of C-terminal deletion mutant of human Cx43/GJA1 (Cx43-M257) in lipid nanodiscs (POPE)
Fitted models: 7xqj
Deposition Authors: Lee HJ
,
Cha HJ
,
Jeong H
,
Lee SN
,
Lee CW,
Woo JS
Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM.
Lee HJ
,
Cha HJ
,
Jeong H
,
Lee SN
,
Lee CW,
Kim M
,
Yoo J,
Woo JS
(2023) Nat Commun , 14 , 931 - 931
,
Cha HJ
,
Jeong H
,
Lee SN
,
Lee CW,
Kim M
,
Yoo J,
Woo JS
(2023) Nat Commun , 14 , 931 - 931
Grant Support:
- National Research Foundation (NRF, Korea): NRF-2018R1C1B6004447 (Korea, Republic Of)
