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EMD-33396

Single-particle
3.8 Å
EMD-33396
3D View Gallery
Deposition: 07/05/2022
Map released: 25/01/2023
Last modified: 30/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-33396
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7xqh summary report (pdf.gz) Map and 7xqh FULL report (pdf.gz)
EMICSS annotations (xml)

Hemichannel-focused structure of C-terminal truncated connexin43/Cx43/GJA1 gap junction intercellular channel in POPE nanodiscs (GCN-TM1i conformation)

EMD-33396

Single-particle
3.8 Å
EMD-33396
3D View Gallery
Deposition: 07/05/2022
Map released: 25/01/2023
Last modified: 30/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Dodecameric complex of C-terminal deletion mutant of human Cx43/GJA1 (Cx43-M257) in lipid nanodiscs (POPE)
Fitted models: 7xqh

Deposition Authors: Lee HJ , Cha HJ , Jeong H , Lee SN , Lee CW, Woo JS
Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM.
Lee HJ , Cha HJ , Jeong H , Lee SN , Lee CW, Kim M , Yoo J, Woo JS
(2023) Nat Commun , 14 , 931 - 931
PUBMED: 36805660
DOI: doi:10.1038/s41467-023-36593-y
ISSN: 2041-1723