Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-33332

Helical reconstruction
3.0 Å
EMD-33332
3D View Gallery
Deposition: 30/04/2022
Map released: 30/11/2022
Last modified: 03/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-33332
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7xo0 summary report (pdf.gz) Map and 7xo0 FULL report (pdf.gz)
EMICSS annotations (xml)

Minor polymorph inalpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-1) Parkinson's disease patient

EMD-33332

Helical reconstruction
3.0 Å
EMD-33332
3D View Gallery
Deposition: 30/04/2022
Map released: 30/11/2022
Last modified: 03/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Minor polymorph inalpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-1) Parkinson's disease patient
Fitted models: 7xo0

Deposition Authors: Fan Y , Sun YP, Wang J, Liu C
Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Fan Y , Sun Y, Yu W, Tao Y, Xia W, Liu Y, Zhao Q, Tang Y, Sun Y, Liu F, Cao Q, Wu J, Liu C, Wang J, Li D
(2023) Structure , 31 , 78
PUBMED: 36513068
DOI: doi:10.1016/j.str.2022.11.013
ISSN: 0969-2126
ASTM: STRUE6