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EMD-33146

Single-particle
2.72 Å
EMD-33146
3D View Gallery
Deposition: 27/03/2022
Map released: 29/03/2023
Last modified: 17/09/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-33146
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7xdf summary report (pdf.gz) Map and 7xdf FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structures of human mitochondrial NAD(P)+-dependent malic enzyme in a ternary complex with NAD+ and allosteric inhibitor EA

EMD-33146

Single-particle
2.72 Å
EMD-33146
3D View Gallery
Deposition: 27/03/2022
Map released: 29/03/2023
Last modified: 17/09/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: human mitochondrial NAD(P)+-dependent malic enzyme in a ternary complex with NAD+ and allosteric inhibitor EA
Fitted models: 7xdf

Deposition Authors: Wang CH, Hsieh JT, Ho MC, Hung HC
Suppression of the human malic enzyme 2 modifies energy metabolism and inhibits cellular respiration
Hsieh JY, Chen KC, Wang CH, Liu GY, Ye JA, Chou YT, Lin YC, Lyu CJ, Chang RY, Liu YL, Li YH, Lee MR, Ho MC, Hung HC
(2023) Commun Biol , 6 , 548
DOI: doi:10.1038/s42003-023-04930-y
ISSN: 2399-3642