EMD-33127

Single-particle
2.72 Å
EMD-33127
3D View Gallery
Deposition: 25/03/2022
Map released: 20/04/2022
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-33127

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7xct summary report (pdf.gz) Map-7xct FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of Dot1L and H2BK34ub-H3K79Nle nucleosome 2:1 complex

EMD-33127

Single-particle
2.72 Å
EMD-33127
3D View Gallery
Deposition: 25/03/2022
Map released: 20/04/2022
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Complex of Dot1L(1-416) and H2BK34ub 2:1 nucleosome
Fitted models: 7xct

Deposition Authors: Ai HS, Liu AJ, Lou ZY, Liu L
H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity.
Ai H, Sun M, Liu A, Sun Z, Liu T, Cao L, Liang L, Qu Q, Li Z, Deng Z, Tong Z, Chu G, Tian X, Deng H, Zhao S, Li JB, Lou Z, Liu L
(2022) Nat Chem Biol , 18 , 972 - 980
PUBMED: 35739357
DOI: doi:10.1038/s41589-022-01067-7
ISSN: 1552-4469