Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-33124

Single-particle
2.5 Å
EMD-33124
3D View Gallery
Deposition: 24/03/2022
Map released: 21/09/2022
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-33124
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7xco summary report (pdf.gz) Map and 7xco FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of SARS-CoV-2 Omicron spike protein (S-6P-RRAR) in complex with S309 fab

EMD-33124

Single-particle
2.5 Å
EMD-33124
3D View Gallery
Deposition: 24/03/2022
Map released: 21/09/2022
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Severe acute respiratory syndrome coronavirus 2
Sample: Cryo-EM structure of SARS-CoV-2 Omicron spike protein in complex with S309 fab
Fitted models: 7xco

Deposition Authors: Gao GF, Qi JX, Zhao ZN, Liu S, Xie YF
Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape
Zhao Z, Zhou J, Tian M, Huang M, Liu S, Xie Y, Han P, Bai C, Han P, Zheng A, Fu L, Gao Y, Peng Q, Li Y, Chai Y, Zhang Z, Zhao X, Song H, Qi J, Wang Q, Wang P, Gao GF
(2022) Nat Commun , 13 , 4958
DOI: doi:10.1038/s41467-022-32665-7
ISSN: 2041-1723
Grant Support: