Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-33103
Cryo-EM structure of human galanin receptor 2
EMD-33103
Single-particle3.11 Å
Deposition: 21/03/2022Map released: 13/07/2022
Last modified: 06/11/2024
Sample Organism:
Homo sapiens,
Mus musculus
Sample: Human galanin receptor 2 complex with Gq heterotrimer
Fitted models: 7xbd
Deposition Authors: Ishimoto N
,
Kita S,
Park SY
Sample: Human galanin receptor 2 complex with Gq heterotrimer
Fitted models: 7xbd
Deposition Authors: Ishimoto N
,
Kita S,
Park SY
Structure of the human galanin receptor 2 bound to galanin and Gq reveals the basis of ligand specificity and how binding affects the G-protein interface.
Heo Y ,
Ishimoto N ,
Jeon YE,
Yun JH ,
Ohki M,
Anraku Y ,
Sasaki M,
Kita S,
Fukuhara H,
Ikuta T ,
Kawakami K ,
Inoue A,
Maenaka K,
Tame JRH ,
Lee W,
Park SY
(2022) PLoS Biol , 20 , e3001714 - e3001714
,
Ishimoto N ,
Jeon YE,
Yun JH ,
Ohki M,
Anraku Y ,
Sasaki M,
Kita S,
Fukuhara H,
Ikuta T ,
Kawakami K ,
Inoue A,
Maenaka K,
Tame JRH ,
Lee W,
Park SY
(2022) PLoS Biol , 20 , e3001714 - e3001714
Grant Support: