Electron Microscopy Data Bank

EMD-32835

Single-particle
20.6 Å

3D View Gallery

Deposition: 08/02/2022
Map released: 08/06/2022
Last modified: 13/12/2023

Overview 3D View Sample Experiment Validation Additional data Links

EMD-32835

Gid12 bound Cage-GIDSR3

EMD-32835

Single-particle
20.6 Å
EMD-32835

3D View Gallery

Deposition: 08/02/2022
Map released: 08/06/2022
Last modified: 13/12/2023

Overview 3D View Sample Experiment Validation Additional data Links

Sample Organism: Saccharomyces cerevisiae
Sample: Gid12-Cage-GIDSR4

Deposition Authors: Qiao S , Cheng DJ , Schulman BA

Cryo-EM structures of Gid12-bound GID E3 reveal steric blockade as a mechanism inhibiting substrate ubiquitylation.

Qiao S , Lee CW , Sherpa D , Chrustowicz J , Cheng J , Duennebacke M, Steigenberger B, Karayel O , Vu DT, von Gronau S, Mann M , Wilfling F , Schulman BA
(2022) Nat Commun , 13 , 3041 - 3041

PUBMED: 35650207
DOI: doi:10.1038/s41467-022-30803-9
ISSN: 2041-1723

Secondary citations:

Sherpa D, Chrustowicz J, Qiao S, Langlois CR, Hehl LA, Gottemukkala KV, Hansen FM, Karayel O, von Gronau S, Prabu JR, Mann M, Alpi AF & Schulman BA. (2021) GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme. Mol Cell, 81, 2445 - 2459.e13

Grant Support:

Max Planck Society: (Germany)

EMD-32835

EMD-32835

Archive Files (Depositor)

Validation (wwPDB)

EMDB Annotations

Gid12 bound Cage-GIDSR3

EMD-32835