Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-32768

Single-particle
4.5 Å
EMD-32768
3D View Gallery
Deposition: 01/02/2022
Map released: 16/02/2022
Last modified: 16/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-32768
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7wsv summary report (pdf.gz) Map and 7wsv FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of the N-terminal deletion mutant of human pannexin-1 in a nanodisc

EMD-32768

Single-particle
4.5 Å
EMD-32768
3D View Gallery
Deposition: 01/02/2022
Map released: 16/02/2022
Last modified: 16/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Heptamar of N-terminal deleted human pannexin-1 in a nanodisc
Fitted models: 7wsv

Deposition Authors: Kuzuya M , Hirano H
Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids.
Kuzuya M , Hirano H, Hayashida K, Watanabe M , Kobayashi K, Terada T , Mahmood MI , Tama F , Tani K , Fujiyoshi Y , Oshima A
(2022) Sci Signal , 15 , eabg6941 - eabg6941
PUBMED: 35133866
DOI: doi:10.1126/scisignal.abg6941
ISSN: 1937-9145