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EMD-32599

Single-particle
3.2 Å
EMD-32599
3D View Gallery
Deposition: 14/01/2022
Map released: 25/01/2023
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-32599
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7wm4 summary report (pdf.gz) Map and 7wm4 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of tetrameric TLR3 in complex with dsRNA (90 bp)

EMD-32599

Single-particle
3.2 Å
EMD-32599
3D View Gallery
Deposition: 14/01/2022
Map released: 25/01/2023
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, synthetic construct
Sample: Tetrameric TLR3 in complex with dsRNA (90 bp)
Fitted models: 7wm4

Deposition Authors: Sakaniwa K, Ohto U
TLR3 forms a laterally aligned multimeric complex along double-stranded RNA for efficient signal transduction.
Sakaniwa K, Fujimura A, Shibata T , Shigematsu H , Ekimoto T, Yamamoto M, Ikeguchi M, Miyake K , Ohto U , Shimizu T
(2023) Nat Commun , 14 , 164 - 164
PUBMED: 36631495
DOI: doi:10.1038/s41467-023-35844-2
ISSN: 2041-1723