Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-32425

Single-particle
2.87 Å
EMD-32425 Deposition: 20/12/2021
Map released: 21/12/2022
Last modified: 18/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-32425

Cryo-EM structure of GPR119-Gs Complex with small molecule agonist AR231453

EMD-32425

Single-particle
2.87 Å
EMD-32425 Deposition: 20/12/2021
Map released: 21/12/2022
Last modified: 18/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: Cryo-EM structure of GPR119-Gs Complex with small molecule agonist AR231453
Fitted models: 7wcn

Deposition Authors: Qiao AN, Wu S , Ye S
Activation and signaling mechanism revealed by GPR119-G s complex structures.
Qian Y, Wang J, Yang L, Liu Y, Wang L, Liu W, Lin Y, Yang H, Ma L , Ye S, Wu S , Qiao A
(2022) Nat Commun , 13 , 7033 - 7033
PUBMED: 36396650
DOI: doi:10.1038/s41467-022-34696-6
ISSN: 2041-1723